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Monday, November 25, 2024

Wearable ultrasound tech for muscle monitoring opens new prospects in healthcare and human-machine interfaces


Engineers on the College of California San Diego have developed a wearable ultrasound gadget that may present long-term, wi-fi monitoring of muscle exercise with potential functions in healthcare and human-machine interfaces. Designed to stay to the pores and skin with a layer of adhesive and powered by a battery, the gadget permits high-resolution monitoring of muscle operate with out invasive procedures.

A staff of researchers led by Sheng Xu, a professor and Jacobs School Scholar within the Aiiso Yufeng Li Household Division of Chemical and Nano Engineering at UC San Diego, revealed their work Oct. 31 in Nature Electronics. The work was a collaborative undertaking with Jinghong Li, a pulmonologist, intensive care specialist and professor of medication at UC San Diego Well being.

In checks, the gadget was worn over the rib cage to observe diaphragm movement and thickness, that are helpful for assessing respiratory well being. “By monitoring diaphragm exercise, the know-how might probably assist sufferers with respiratory circumstances and people reliant on mechanical air flow,” mentioned Joseph Wang, a distinguished professor within the Aiiso Yufeng Li Household Division of Chemical and Nano Engineering who’s a co-author on the research.

Moreover, researchers efficiently used the gadget on the forearm to seize hand and wrist muscle exercise, which enabled its use as a human-machine interface to regulate a robotic arm and play a digital sport.

This wearable ultrasound know-how might provide a promising new various to the present medical normal, electromyography (EMG), which entails making use of steel electrodes on the pores and skin to document electrical muscle exercise. Regardless of EMG’s longstanding use, it suffers from low decision and weak indicators. For instance, indicators from a number of muscle fibers typically mix collectively, making it difficult to isolate the contributions of particular muscle fibers.

Ultrasound, nonetheless, offers high-resolution imaging by penetrating deep tissues, providing detailed insights into muscle operate. The ultrasound know-how that Xu’s staff and their collaborators developed has the extra benefits of being compact, wi-fi, and low-power. “This know-how might probably be worn by people throughout their each day routines for steady, long-term monitoring,” mentioned research co-first writer Xiangjun Chen, a Ph.D candidate within the Supplies Science and Engineering program at UC San Diego.

The gadget is housed in a versatile silicone elastomer casing and consists of three foremost elements: a single transducer for sending and receiving ultrasound waves; a custom-designed wi-fi circuit that controls the transducer, data knowledge and wirelessly transmits the information to a pc; and a lithium-polymer battery that may energy the system for a minimum of three hours.

A key innovation of this work is using a single ultrasound transducer to sense deep tissues successfully. The transducer emits intensity-controlled ultrasound waves and captures radiofrequency indicators that carry wealthy info, enabling medical functions akin to measuring diaphragm thickness. Utilizing these indicators, the gadget can obtain excessive spatial decision, which is vital for isolating particular muscle actions. To extract further insights from these indicators, the researchers developed a man-made intelligence algorithm that maps the indicators to their corresponding muscle distributions, enabling it to determine particular hand gestures from the collected indicators with excessive accuracy and reliability.

When worn on the rib cage, the gadget can precisely monitor diaphragm thickness with submillimeter precision. Diaphragm thickness is a metric used within the clinic to guage diaphragm dysfunction and predict outcomes in ventilated sufferers. By analyzing muscle movement, the researchers might additionally detect totally different respiratory patterns, akin to shallow and deep breaths. This performance might assist diagnose circumstances linked to respiratory irregularities, akin to bronchial asthma, pneumonia and persistent obstructive pulmonary illness (COPD). In a small group trial, the gadget efficiently distinguished respiratory patterns of people with COPD from these of wholesome contributors.

“This demonstrates the know-how’s potential for medical functions in respiratory care,” mentioned research co-first writer Muyang Lin, a postdoctoral researcher within the Aiiso Yufeng Li Household Division of Chemical and Nano Engineering at UC San Diego.

When worn on the forearm, the gadget presents exact monitoring of muscle movement within the palms and wrists. Due to the unreal intelligence algorithm that the staff developed, the system is able to recognizing varied hand gestures solely from the ultrasound indicators. The system is ready to acknowledge 13 levels of freedom, overlaying 10 finger joints and three rotation angles of the wrist. In consequence, it will possibly seize even slight wrist and finger actions with excessive sensitivity.

In proof-of-concept checks, contributors used the gadget on their forearms to regulate a robotic arm to pipette water into beakers. In one other demonstration, they used the gadget to play a digital sport, utilizing wrist actions to regulate a digital chicken’s flight by way of obstacles. “These demonstrations underscore the know-how’s potential for prosthetics, gaming and different human-machine interface functions,” mentioned research co-first writer Wentong Yue, a Ph.D. candidate within the Aiiso Yufeng Li Household Division of Chemical and Nano Engineering at UC San Diego.

Shifting ahead, the researchers plan to enhance the know-how’s accuracy, portability, power effectivity and computational capabilities.

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