Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. World most cancers statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 nations. CA Most cancers J Clin. 2018;68(6):394–424.
Zhou J, Solar H, Wang Z, Cong W, Zeng M, Zhou W, Bie P, Liu L, Wen T, Kuang M, Han G, Yan Z, Wang M, Liu R, Lu L, Ren Z, Zeng Z, Liang P, Liang C, Chen M, Yan F, Wang W, Hou J, Ji Y, Yun J, Bai X, Cai D, Chen W, Chen Y, Cheng W, Cheng S, Dai C, Guo W, Guo Y, Hua B, Huang X, Jia W, Li Q, Li T, Li X, Li Y, Li Y, Liang J, Ling C, Liu T, Liu X, Lu S, Lv G, Mao Y, Meng Z, Peng T, Ren W, Shi H, Shi G, Shi M, Music T, Tao Okay, Wang J, Wang Okay, Wang L, Wang W, Wang X, Wang Z, Xiang B, Xing B, Xu J, Yang J, Yang J, Yang Y, Yang Y, Ye S, Yin Z, Zeng Y, Zhang B, Zhang B, Zhang L, Zhang S, Zhang T, Zhang Y, Zhao M, Zhao Y, Zheng H, Zhou L, Zhu J, Zhu Okay, Liu R, Shi Y, Xiao Y, Zhang L, Yang C, Wu Z, Dai Z, Chen M, Cai J, Wang W, Cai X, Li Q, Shen F, Qin S, Teng G, Dong J, Fan J. Liver Most cancers. 2023;12(5):405–44. Pointers for the Prognosis and Remedy of Main Liver Most cancers (2022 Version).
Wang Y, Jiang L, Zhang Y, Lu Y, Li J, Wang H, Yao D, Wang D. Fibronectin-targeting and cathepsin B-Activatable theranostic nanoprobe for MR/Fluorescence Imaging and enhanced photodynamic remedy for Triple damaging breast Most cancers. ACS Appl Mater Interfaces. 2020;12(30):33564–74.
de Feria Cardet RE, Hofman MS, Segard T, Yim J, Williams S, Francis RJ, Frydenberg M, Lawrentschuk N, Murphy DG, De Abreu Lourenco R. Is prostate-specific membrane Antigen Positron Emission Tomography/Computed Tomography Imaging cost-effective in prostate Most cancers: an evaluation knowledgeable by the proPSMA trial. Eur Urol. 2021;79(3):413–8.
Fraum TJ, Ludwig DR, Bashir MR, Fowler KJ. Gadolinium-based distinction brokers: a complete threat evaluation. J Magn Reson Imaging. 2017;46(2):338–53.
Ng TSC, Garlin MA, Weissleder R, Miller MA. Bettering nanotherapy supply and motion by way of image-guided methods pharmacology. Theranostics. 2020;10:968–97.
Wang D, Zhang N, Jing X, et al. A tumor-micro setting totally responsive nano-platform for MRI-guided photograph dynamic and photothermal synergistic remedy. J Mater Chem B. 2020;8:8271–81.
Correa S, Boehnke N, Deiss-Yehiely E, Hammond PT. Resolution situations Tune and optimize loading of therapeutic polyelectrolytes into layer-by-layer Functionalized Liposomes. ACS Nano. 2019;13:5623–34.
Kciuk M, Gielecińska A, Mujwar S, Kołat D, Kałuzińska-Kołat Ż, Celik I, Kontek R. Doxorubicin-An Agent with a number of mechanisms of Anticancer Exercise. Cells. 2023;12(4):659.
Li DL, Wang ZV, Ding G, Tan W, Luo X, Criollo A, Xie M, Jiang N, Could H, Kyrychenko V, Schneider JW, Gillette TG, Hill JA. Doxorubicin blocks Cardiomyocyte Autophagic Flux by inhibiting lysosome acidification. Circulation. 2016;133(17):1668–87.
Cersosimo RJ, Hong WK. Epirubicin: a assessment of the pharmacology, medical exercise, and hostile results of an adriamycin analogue. J Clin Oncol. 1986;4(3):425–39.
Forner A, Reig M, Bruix J. Hepatocellular carcinoma. Lancet. 2018;391(10127):1301–14.
Barenholz Y. Doxil®–the first FDA-approved nano-drug: classes realized. J Management Launch. 2012;160(2):117–34.
Wang L, Luo R, Onyshchenko Okay, Rao X, Wang M, Menz B, Gaedicke S, Grosu AL, Firat E, Niedermann G. Including liposomal doxorubicin enhances the abscopal impact induced by radiation/αPD1 remedy relying on tumor cell mitochondrial DNA and cGAS/STING. J Immunother Most cancers. 2023;11(8):e006235.
Lei Q, Wang SB, Hu JJ, Lin YX, Zhu CH, Rong L, Zhang XZ. Stimuli-Responsive Cluster Bomb for programmed Tumor Remedy. ACS Nano. 2017;11(7):7201–14.
Qi G, Shi G, Wang S, Hu H, Zhang Z, Yin Q, Li Z, Hao L. A novel pH-Responsive Iron Oxide Core-Shell magnetic mesoporous silica nanoparticle (M-MSN) System Encapsulating Doxorubicin (DOX) and glucose oxidase (gox) for pancreatic Most cancers therapy. Int J Nanomed. 2023;18:7133–47.
Zhang Y, Cai Okay, Li C, Guo Q, Chen Q, He X, Liu L, Zhang Y, Lu Y, Chen X, Solar T, Huang Y, Cheng J, Jiang C. Macrophage-membrane-coated nanoparticles for Tumor-targeted chemotherapy. Nano Lett. 2018;18(3):1908–15.
Tao W, Wang J, Parak WJ, Farokhzad OC, Shi J. Nanobuffering of pH-Responsive polymers: a identified however typically neglected Phenomenon and its organic purposes. ACS Nano. 2019;13(5):4876–82.
Cheng R, Jiang L, Gao H, Liu Z, Mäkilä E, Wang S, Saiding Q, Xiang L, Tang X, Shi M, Liu J, Pang L, Salonen J, Hirvonen J, Zhang H, Cui W, Shen B, Santos HA. A pH-Responsive Cluster Metallic-Natural Framework nanoparticle for enhanced Tumor Accumulation and Antitumor Impact. Adv Mater. 2022;34(42):e2203915.
Schulze RJ, Krueger EW, Weller SG, et al. Direct lysosome-based autophagy of lipid droplets in hepatocytes. Proc Natl Acad Sci U S A. 2020;117(51):32443–52.
Mizushima N, Komatsu M. Autophagy: renovation of cells and tissues. Cell. 2011;147(4):728–41.
Onorati AV, Dyczynski M, Ojha R, Amaravadi RK. Focusing on autophagy in most cancers. Most cancers. 2018;124(16):3307–18.
Zhang Z, Yu Y, Zhang Z, Li D, Liang Z, Wang L, Chen Y, Liang Y, Niu H. Most cancers-associated fibroblasts-derived CXCL12 enhances immune escape of bladder most cancers by way of inhibiting P62-mediated autophagic degradation of PDL1. J Exp Clin Most cancers Res. 2023;42(1):316.
Wang S, Guo R, Su Y, Yang C, Guo Y, Tan C, Zhao B. Swainsonine promotes apoptosis by impairing lysosomal operate and inhibiting autophagic degradation in rat major renal tubular epithelial cells. Chem Biol Work together. 2021;336:109319.
He Okay, Li J, Shen Y, Yu Y. pH-Responsive polyelectrolyte coated gadolinium oxide-doped mesoporous silica nanoparticles (Gd2O3@MSNs) for synergistic drug supply and magnetic resonance imaging enhancement. J Mater Chem B. 2019;7(43):6840–54.
Wang Y, Gao W, Shi X, Ding J, Liu W, He H, Wang Okay, Shao F. Chemotherapy medicine induce pyroptosis by way of caspase-3 cleavage of a gasdermin. Nature. 2017;547(7661):99–103.
Eskelinen EL. Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and autophagy. Mol Features Med. 2006;27(5–6):495–502.
Armenta DA, Laqtom NN, Alchemy G, Dong W, Morrow D, Poltorack CD, Nathanson DA, Abu-Remalieh M, Dixon SJ. Ferroptosis inhibition by lysosome-dependent catabolism of extracellular protein. Cell Chem Biol. 2022;29(11):1588–e16007.
Feng L, Liang L, Zhang S, Yang J, Yue Y, Zhang X. HMGB1 downregulation in retinal pigment epithelial cells protects in opposition to diabetic retinopathy by way of the autophagy-lysosome pathway. Autophagy. 2022;18(2):320–39.
Mariño G, Niso-Santano M, Baehrecke EH, Kroemer G. Self-consumption: the interaction of autophagy and apoptosis. Nat Rev Mol Cell Biol. 2014;15(2):81–94.
Amaravadi R, Kimmelman AC, White E. Current insights into the operate of autophagy in most cancers. Genes Dev. 2016;30(17):1913–30.
Jain V, Singh MP, Amaravadi RK. Current advances in concentrating on autophagy in most cancers. Developments Pharmacol Sci. 2023;44(5):290–302.
Mahalingam D, Mita M, Sarantopoulos J, Wooden L, Amaravadi RK, Davis LE, Mita AC, Curiel TJ, Espitia CM, Nawrocki ST, Giles FJ, Carew JS. Mixed autophagy and HDAC inhibition: a section I security, tolerability, pharmacokinetic, and pharmacodynamic evaluation of hydroxychloroquine together with the HDAC inhibitor vorinostat in sufferers with superior strong tumors. Autophagy. 2014;10(8):1403–14.
Al-Hajm AYS, Ozgun E. Results of acrylamide on protein degradation pathways in human liver-derived cells and the efficacy of N-acetylcysteine and curcumin. Drug Chem Toxicol. 2022;45(4):1536–43.
Liu GY, Sabatini DM. mTOR on the nexus of diet, progress, ageing and illness. Nat Rev Mol Cell Biol. 2020;21(4):183–203.
Xie Y, Zhao G, Lei X, Cui N, Wang H. Advances within the regulatory mechanisms of mTOR in necroptosis. Entrance Immunol. 2023;14:1297408.
Sardiello M. Transcription issue EB: from grasp coordinator of lysosomal pathways to candidate therapeutic goal in degenerative storage ailments. Ann N Y Acad Sci. 2016;1371(1):3–14.
Settembre C, Di Malta C, Polito VA, Garcia Arencibia M, Vetrini F, Erdin S, Erdin SU, Huynh T, Medina D, Colella P, Sardiello M, Rubinsztein DC, Ballabio A. TFEB hyperlinks autophagy to lysosomal biogenesis. Science. 2011;332(6036):1429–33.
Yang CT, Hattiholi A, Selvan ST, Yan SX, Fang WW, Chandrasekharan P, Koteswaraiah P, Herold CJ, Gulyás B, Aw SE, He T, Ng DCE, Padmanabhan P. Gadolinium-based bimodal probes to boost T1-Weighted magnetic resonance/optical imaging. Acta Biomater. 2020;110:15–36.
Li X, Zhao W, Liu X, Chen Okay, Zhu S, Shi P, Chen Y, Shi J. Mesoporous manganese silicate coated silica nanoparticles as multi-stimuli-responsive T1-MRI distinction brokers and drug supply carriers. Acta Biomater. 2016;30:378–87.
Li L, Guan Y, Liu H, Hao N, Liu T, Meng X, Fu C, Li Y, Qu Q, Zhang Y, Ji S, Chen L, Chen D, Tang F. Silica nanorattle-doxorubicin-anchored mesenchymal stem cells for tumor-tropic remedy. ACS Nano. 2011;5(9):7462–70.