Lengthy Q, Zhou W, Zhou H, Tang Y, Chen W, Liu Q, Bian X. Polyamine-containing pure merchandise: construction, bioactivity, and biosynthesis. Nat Prod Rep. 2024;41:525–64.
Baunach M, Guljamow A, Miguel-Gordo M, Dittmann E. Harnessing the potential: advances in cyanobacterial pure product analysis and biotechnology. Nat Prod Rep. 2024;41:347–69.
Kong X, Liu C, Zhang Z, Cheng M, Mei Z, Li X, Liu P, Diao L, Ma Y, Jiang P, et al. BATMAN-TCM 20: an enhanced integrative database for identified and predicted interactions between conventional Chinese language medication elements and goal proteins. Nucleic Acids Res. 2024;52:1110–20.
Zhang J, Pang H, Tang H, Tu Q, Xia F, Zhang H, Meng Y, Han G, Wang J, Qiu C. The pharmacodynamic and pharmacological mechanisms underlying nanovesicles of pure merchandise: developments and challenges. Pharmacol Ther. 2025;265: 108754.
Guo X, Luo W, Wu L, Zhang L, Chen Y, Li T, Li H, Zhang W, Liu Y, Zheng J, Wang Y. Pure merchandise from natural medication self-assemble into superior bioactive supplies. Adv Sci. 2024;11: e2403388.
Xu Ok, Ren X, Wang J, Zhang Q, Fu X, Zhang PC. Medical improvement and informatics evaluation of pure and semi-synthetic flavonoid medicine: a crucial evaluation. J Adv Res. 2024;63:269–84.
Huang Ok, Zhang P, Zhang Z, Youn JY, Wang C, Zhang H, Cai H. Conventional Chinese language medication (TCM) within the therapy of COVID-19 and different viral infections: efficacies and mechanisms. Pharmacol Ther. 2021;225: 107843.
Solar R, Dai J, Ling M, Yu L, Yu Z, Tang L. Supply of triptolide: a mixture of conventional Chinese language medication and nanomedicine. J Nanobiotechnol. 2022;20:194.
Ran B, Ren X, Lin X, Teng Y, Xin F, Ma W, Zhao X, Li M, Wang J, Wang C, et al. Glycyrrhetinic acid loaded in milk-derived extracellular vesicles for inhalation remedy of idiopathic pulmonary fibrosis. J Management Launch. 2024;370:811–20.
Zhang S, Zhou R, Xie X, Xiong S, Li L, Li Y. Polysaccharides from Lycium barbarum, yam, and sunflower ameliorate colitis in a construction and intrinsic flora-dependent method. Carbohydr Polym. 2025;349: 122905.
Ji R, Wang Z, Kuang H. Extraction, purification, structural characterization, and organic exercise of polysaccharides from Schisandra chinensis: a evaluation. Int J Biol Macromol. 2024;271: 132590.
Mao Q, Min J, Zeng R, Liu H, Li H, Zhang C, Zheng A, Lin J, Liu X, Wu M. Self-assembled conventional Chinese language nanomedicine modulating tumor immunosuppressive microenvironment for colorectal most cancers immunotherapy. Theranostics. 2022;12:6088–105.
Yang C, Li D, Ko CN, Wang Ok, Wang H. Lively elements of conventional Chinese language medication for enhancing the impact of tumor immunotherapy. Entrance Immunol. 2023;14:1133050.
Wang Y, Zhang Q, Chen Y, Liang CL, Liu H, Qiu F, Dai Z. Antitumor results of immunity-enhancing conventional Chinese language medication. Biomed Pharmacother. 2020;121: 109570.
Bu L, Dai O, Zhou F, Liu F, Chen JF, Peng C, Xiong L. Conventional Chinese language medication formulation, extracts, and compounds promote angiogenesis. Biomed Pharmacother. 2020;132: 110855.
Zhang X, Qiu H, Li C, Cai P, Qi F. The optimistic position of conventional Chinese language medication as an adjunctive remedy for most cancers. Biosci Developments. 2021;15:283–98.
Zheng Y, Wang Y, Xia M, Gao Y, Zhang L, Music Y, Zhang C. The mix of nanotechnology and conventional Chinese language medication (TCM) evokes the modernization of TCM: evaluation on nanotechnology in TCM-based drug supply techniques. Drug Deliv Transl Res. 2022;12:1306–25.
Zeng Q, Chen H, Wang Z, Guo Y, Wu Y, Hu Y, Liang P, Zheng Z, Liang T, Zhai D, et al. Provider-free cryptotanshinone-peptide conjugates self-assembled nanoparticles: an environment friendly and low-risk technique for pimples vulgaris. Asian J Pharm Sci. 2024;19: 100946.
Kan G, Chen L, Zhang W, Bian Q, Wang X, Zhong J. Latest advances within the improvement and utility of curcumin-loaded micro/nanocarriers in meals analysis. Adv Colloid Interface Sci. 2025;335: 103333.
Zdrojewicz Z, Waracki M, Bugaj B, Pypno D, Cabala Ok. Medical purposes of nanotechnology. Postepy Hig Med Dosw. 2015;69:1196–204.
Barrett T, Ravizzini G, Choyke PL, Kobayashi H. Dendrimers in medical nanotechnology. IEEE Eng Med Biol Magazine. 2009;28:12–22.
Zhu L, Torchilin VP. Stimulus-responsive nanopreparations for tumor concentrating on. Integr Biol (Camb). 2013;5:96–107.
Zou B, Lengthy Y, Gao R, Liu Q, Tian X, Liu B, Zhou Q. Nanodelivery system of conventional Chinese language medication bioactive compounds: utility within the therapy of prostate most cancers. Phytomedicine. 2024;135: 155554.
Nath D, Banerjee P. Inexperienced nanotechnology—a brand new hope for medical biology. Environ Toxicol Pharmacol. 2013;36:997–1014.
Liu H, Luo GF, Shang Z. Plant-derived nanovesicles as an rising platform for most cancers remedy. Acta Pharm Sin B. 2024;14:133–54.
Huang Y, Zhao Y, Liu F, Liu S. Nano conventional Chinese language medication: present progresses and future challenges. Curr Drug Targets. 2015;16:1548–62.
Rahman HS, Othman HH, Hammadi NI, Yeap SK, Amin KM, Abdul Samad N, Alitheen NB. Novel drug supply techniques for loading of pure plant extracts and their biomedical purposes. Int J Nanomed. 2020;15:2439–83.
Guan J, Chen W, Yang M, Wu E, Qian J, Zhan C. Regulation of in vivo supply of nanomedicines by natural medicines. Adv Drug Deliv Rev. 2021;174:210–28.
Qiu C, Zhang JZ, Wu B, Xu CC, Pang HH, Tu QC, Lu YQ, Guo QY, Xia F, Wang JG. Superior utility of nanotechnology in lively constituents of conventional Chinese language medicines. J Nanobiotechnology. 2023;21:456.
Liu X, Zhao Y, Liang X, Ding Y, Hu J, Deng N, Zhao Y, Huang P, Xie W. In Vivo analysis of self-assembled nano-saikosaponin-a for epilepsy therapy. Mol Biotechnol. 2023;66:2230–40.
Fu S, Yang X. Latest advances in pure small molecules as drug supply techniques. J Mater Chem B. 2023;11:4584–99.
Northrop BH, Zheng YR, Chi KW, Stang PJ. Self-organization in coordination-driven self-assembly. Acc Chem Res. 2009;42:1554–63.
Luo QW, Yao L, Li L, Yang Z, Zhao MM, Zheng YZ, Zhuo FF, Liu TT, Zhang XW, Liu D, et al. Inherent functionality of self-assembling nanostructures in particular proteasome activation for most cancers cell pyroptosis. Small. 2023;19: e2205531.
Wu Z, Li H, Zhao X, Ye F, Zhao G. Hydrophobically modified polysaccharides and their self-assembled techniques: a evaluation on buildings and meals purposes. Carbohydr Polym. 2022;284: 119182.
Li J, Wu D, Su Z, Guo J, Cui L, Su H, Chen Y, Yu B. Zinc-induced photocrosslinked konjac glucomannan/glycyrrhizic acid hydrogel promotes pores and skin wound therapeutic in diabetic mice by way of immune regulation. Carbohydr Polym. 2025;348: 122780.
Liu X, Liu S, Jin X, Liu H, Solar Ok, Wang X, Li M, Wang P, Chang Y, Wang T, et al. An encounter between steel ions and pure merchandise: pure products-coordinated steel ions for the analysis and therapy of tumors. J Nanobiotechnology. 2024;22:726.
Dai X, Shi X, Wang Y, Qiao Y. Solubilization of saikosaponin a by ginsenoside Ro biosurfactant in aqueous resolution: mesoscopic simulation. J Colloid Interface Sci. 2012;384:73–80.
Xie X, Jiang Ok, Li B, Hou S, Tang H, Shao B, Ping Y, Zhang Q. A small-molecule self-assembled nanodrug for mixture remedy of photothermal-differentiation-chemotherapy of breast most cancers stem cells. Biomaterials. 2022;286: 121598.
Curfman G. Conventional Chinese language medication for ST-segment elevation myocardial infarction. JAMA. 2023;330:1546.
Liu X, Wu Z, Guo C, Guo H, Su Y, Chen Q, Solar C, Liu Q, Chen D, Mu H. Hypoxia responsive nano-drug supply system based mostly on angelica polysaccharide for liver most cancers remedy. Drug Deliv. 2022;29:138–48.
Bisso S, Leroux JC. Nanopharmaceuticals: a give attention to their scientific translatability. Int J Pharm. 2020;578: 119098.
Navashenaq JG, Zamani P, Nikpoor AR, Tavakkol-Afshari J, Jaafari MR. Doxil chemotherapy plus liposomal P5 immunotherapy decreased myeloid-derived suppressor cells in murine mannequin of breast most cancers. Nanomedicine. 2020;24: 102150.
Akinc A, Maier MA, Manoharan M, Fitzgerald Ok, Jayaraman M, Barros S, Ansell S, Du X, Hope MJ, Madden TD, et al. The Onpattro story and the scientific translation of nanomedicines containing nucleic acid-based medicine. Nat Nanotechnol. 2019;14:1084–7.
Wang G, Serkova NJ, Groman EV, Scheinman RI, Simberg D. Feraheme (Ferumoxytol) is acknowledged by proinflammatory and anti inflammatory macrophages by way of scavenger receptor sort AI/II. Mol Pharm. 2019;16:4274–81.
Changxing L, Galani S, Hassan FU, Rashid Z, Naveed M, Fang D, Ashraf A, Qi W, Arif A, Saeed M, et al. Biotechnological approaches to the manufacturing of plant-derived promising anticancer brokers: an replace and overview. Biomed Pharmacother. 2020;132: 110918.
Buisseret L, Loirat D, Aftimos P, Maurer C, Punie Ok, Debien V, Kristanto P, Eiger D, Goncalves A, Ghiringhelli F, et al. Paclitaxel plus carboplatin and durvalumab with or with out oleclumab for girls with beforehand untreated domestically superior or metastatic triple-negative breast most cancers: the randomized SYNERGY part I/II trial. Nat Commun. 2023;14:7018.
Tan X, Zou S, Chen H, Chen D. Comparability of paclitaxel liposomes mixed with carboplatin versus paclitaxel mixed with carboplatin within the therapy of superior ovarian most cancers. J Int Med Res. 2023;51:3000605231200267.
Lin YW, Lin TT, Chen CH, Wang RH, Lin YH, Tseng TY, Zhuang YJ, Tang SY, Lin YC, Pang JY, et al. Enhancing efficacy of albumin-bound paclitaxel for human lung and colorectal cancers by way of autophagy receptor sequestosome 1 (SQSTM1)/p62-mediated nanodrug supply and most cancers remedy. ACS Nano. 2023;17:19033–51.
Moon C, Verschraegen CF, Bevers M, Freedman R, Kudelka AP, Kavanagh JJ. Use of docetaxel (Taxotere) in sufferers with paclitaxel (Taxol) hypersensitivity. Anticancer Medicine. 2000;11:565–8.
Sofias AM, Dunne M, Storm G, Allen C. The battle of “nano” paclitaxel. Adv Drug Deliv Rev. 2017;122:20–30.
Yuan H, Guo H, Luan X, He M, Li F, Burnett J, Truchan N, Solar D. Albumin nanoparticle of paclitaxel (Abraxane) decreases whereas taxol will increase breast most cancers stem cells in therapy of triple detrimental breast most cancers. Mol Pharm. 2020;17:2275–86.
Zhang J, Pan Y, Shi Q, Zhang G, Jiang L, Dong X, Gu Ok, Wang H, Zhang X, Yang N, et al. Paclitaxel liposome for injection (Lipusu) plus cisplatin versus gemcitabine plus cisplatin within the first-line therapy of domestically superior or metastatic lung squamous cell carcinoma: a multicenter, randomized, open-label, parallel managed scientific examine. Most cancers Commun. 2022;42:3–16.
Koudelka S, Turanek J. Liposomal paclitaxel formulations. J Management Launch. 2012;163:322–34.
Parodi A, Kolesova EP, Voronina MV, Frolova AS, Kostyushev D, Trushina DB, Akasov R, Pallaeva T, Zamyatnin AA Jr. Anticancer nanotherapeutics in scientific trials: the work behind scientific translation of nanomedicine. Int J Mol Sci. 2022;23:8.
Ranade AA, Joshi DA, Phadke GK, Patil PP, Kasbekar RB, Apte TG, Dasare RR, Mengde SD, Parikh PM, Bhattacharyya GS, Lopes GL. Medical and financial implications of using nanoparticle paclitaxel (Nanoxel) in India. Ann Oncol. 2013;24(Suppl 5):v6-12.
Ma WW, Zhu M, Lam ET, Diamond JR, Dy GK, Fisher GA, Goff LW, Alberts S, Bui LA, Sanghal A, et al. A part I pharmacokinetic and security examine of paclitaxel injection focus for nano-dispersion (PICN) alone and together with carboplatin in sufferers with superior stable malignancies and biliary tract cancers. Most cancers Chemother Pharmacol. 2021;87:779–88.
Shan X, Gong X, Li J, Wen J, Li Y, Zhang Z. Present approaches of nanomedicines available in the market and varied stage of scientific translation. Acta Pharm Sin B. 2022;12:3028–48.
Wang S, Guo Q, Xu R, Lin P, Deng G, Xia X. Correction: mixture of ferroptosis and pyroptosis twin induction by triptolide nano-MOFs for immunotherapy of melanoma. J Nanobiotechnol. 2024;22:415.
Bao J, Zhang Q, Duan T, Hu R, Tang J. The destiny of nanoparticles In Vivo and the technique of designing stealth nanoparticle for drug supply. Curr Drug Targets. 2021;22:922–46.
Zhong W, Zhang X, Zeng Y, Lin D, Wu J. Latest purposes and methods in nanotechnology for lung illnesses. Nano Res. 2021;14:2067–89.
Solar F, Shen H, Liu Q, Chen Y, Guo W, Du W, Xu C, Wang B, Xing G, Jin Z, et al. Highly effective synergy of conventional Chinese language medication and aggregation-induced emission-active photosensitizer in photodynamic remedy. ACS Nano. 2023;17:18952–64.
Ye Y, Zhong W, Luo R, Wen H, Ma Z, Qi S, Han X, Nie W, Chang D, Xu R, et al. Correction: Thermosensitive hydrogel with emodin-loaded triple-targeted nanoparticles for a rectal drug supply system within the therapy of continual non-bacterial prostatitis. J Nanobiotechnol. 2024;22:259.
Liang J, Wang WF, Zhang Y, Chai YQ, Li YG, Jiang SL, Zhu XH, Guo YL, Wei Z, Solar XZ, et al. Fructooligosaccharides and fructans from platycodon grandiflorum: structural characterization, lung-oriented steerage and targetability. Carbohydr Polym. 2024;323: 121457.
Mitchell MJ, Billingsley MM, Haley RM, Wechsler ME, Peppas NA, Langer R. Engineering precision nanoparticles for drug supply. Nat Rev Drug Discov. 2021;20:101–24.
Chen L, Ming H, Li B, Yang C, Liu S, Gao Y, Zhang T, Huang C, Lang T, Yang Z. Tumor-specific nano-herb supply system with excessive L-arginine loading for synergistic chemo and gasoline remedy towards cervical most cancers. Small. 2024;20:e2403869.
Yang C, Ming H, Li B, Liu S, Chen L, Zhang T, Gao Y, He T, Huang C, Du Z. A pH and glutathione-responsive carbon monoxide-driven nano-herb supply system for enhanced immunotherapy in colorectal most cancers. J Management Launch. 2024;376:659–77.
Jia Y, Yao Y, Fan L, Huang Q, Wei G, Shen P, Solar J, Zhu G, Solar Z, Zhu C, Han X. Tumor microenvironment responsive nano-herb and CRISPR supply system for synergistic chemotherapy and immunotherapy. J Nanobiotechnol. 2024;22:346.
Weng Z, Wei Q, Ye C, Xu Y, Gao J, Zhang W, Liu L, Zhang Y, Hu J, Zhong Q, et al. Conventional herb (Moxa) modified zinc oxide nanosheets for fast, environment friendly and excessive tissue penetration remedy of fungal an infection. ACS Nano. 2024;18:5180–95.
Huang Y, Chen Y, Lu Z, Yu B, Zou L, Music X, Han H, Jin Q, Ji J. Facile synthesis of self-targeted Zn(2+) -gallic acid nanoflowers for particular adhesion and elimination of gram-positive micro organism. Small. 2023;19: e2302578.
Tian S, Su L, Liu Y, Cao J, Yang G, Ren Y, Huang F, Liu J, An Y, van der Mei HC, et al. Self-targeting, zwitterionic micellar dispersants improve antibiotic killing of infectious biofilms-an intravital imaging examine in mice. Sci Adv. 2020;6:eabb1112.
Liao R, Solar ZC, Wang L, Xian C, Lin R, Zhuo G, Wang H, Fang Y, Liu Y, Yang R, et al. Inhalable and bioactive lipid-nanomedicine based mostly on bergapten for focused acute lung harm remedy by way of orchestrating macrophage polarization. Bioact Mater. 2025;43:406–22.
Guo C, Hou X, Liu Y, Zhang Y, Xu H, Zhao F, Chen D. Novel Chinese language angelica polysaccharide biomimetic nanomedicine to curcumin supply for hepatocellular carcinoma therapy and immunomodulatory impact. Phytomedicine. 2021;80: 153356.
Wang DY, Su L, Yang G, Ren Y, Zhang M, Jing H, Zhang X, Bayston R, van der Mei HC, Busscher HJ, Shi L. Self-targeting of zwitterion-based platforms for nano-antimicrobials and nanocarriers. J Mater Chem B. 2022;10:2316–22.
Xiao X, Wang Y, Chen J, Qin P, Chen P, Zhou D, Pan Y. Self-targeting platinum(IV) amphiphilic prodrug nano-assembly as radiosensitizer for synergistic and secure chemoradiotherapy of hepatocellular carcinoma. Biomaterials. 2022;289: 121793.
Shi D, Zhuang J, Fan Z, Zhao H, Zhang X, Su G, Xie L, Ge D, Hou Z. Self-targeting nanotherapy based mostly on functionalized graphene oxide for synergistic thermochemotherapy. J Colloid Interface Sci. 2021;603:70–84.
Yang Y, Guo J, Huang L. Tackling TAMs for most cancers immunotherapy: it’s nano time. Developments Pharmacol Sci. 2020;41:701–14.
Yan C, Li Q, Solar Q, Yang L, Liu X, Zhao Y, Shi M, Li X, Luo Ok. Promising nanomedicines of Shikonin for most cancers remedy. Int J Nanomed. 2023;18:1195–218.
Qu J, Qiu B, Zhang Y, Hu Y, Wang Z, Guan Z, Qin Y, Sui T, Wu F, Li B, et al. The tumor-enriched small molecule gambogic amide suppresses glioma by concentrating on WDR1-dependent cytoskeleton reworking. Sign Transduct Goal Ther. 2023;8:424.
Zhang Y, Li Y, Tian H, Zhu Q, Wang F, Fan Z, Zhou S, Wang X, Xie L, Hou Z. Redox-responsive and dual-targeting hyaluronic acid-methotrexate prodrug self-assembling nanoparticles for enhancing intracellular drug self-delivery. Mol Pharm. 2019;16:3133–44.
Alsudir SA, Almalik A, Alhasan AH. Catalogue of self-targeting nano-medical innovations to speed up scientific trials. Biomater Sci. 2021;9:3898–910.
Mak LY, Liu Ok, Chirapongsathorn S, Yew KC, Tamaki N, Rajaram RB, Panlilio MT, Lui R, Lee HW, Lai JC, et al. Liver illnesses and hepatocellular carcinoma within the Asia-Pacific area: burden, traits, challenges and future instructions. Nat Rev Gastroenterol Hepatol. 2024;21:834–51.
Wu J, Tang G, Cheng CS, Yeerken R, Chan YT, Fu Z, Zheng YC, Feng Y, Wang N. Conventional Chinese language medication for the therapy of cancers of hepatobiliary system: from scientific proof to drug discovery. Mol Most cancers. 2024;23:218.
Wu L, Ma T, Zang C, Xu Z, Solar W, Luo H, Yang M, Music J, Chen S, Yao H. Glycyrrhiza, a generally used medicinal herb: Evaluation of species classification, pharmacology, lively ingredient biosynthesis, and artificial biology. J Adv Res. 2024. https://doi.org/10.1016/j.jare.2024.11.019.
Lv Y, Li J, Chen H, Bai Y, Zhang L. Glycyrrhetinic acid-functionalized mesoporous silica nanoparticles as hepatocellular carcinoma-targeted drug provider. Int J Nanomed. 2017;12:4361–70.
Li R, Zhou J, Zhang X, Wang Y, Wang J, Zhang M, He C, Zhuang P, Chen H. Development of the Gal-NH(2)/mulberry leaf polysaccharides-lysozyme/luteolin nanoparticles and the amelioration results on lipid accumulation. Int J Biol Macromol. 2023;253: 126780.
Wang M, Ma X, Wang G, Music Y, Zhang M, Mai Z, Zhou B, Ye Y, Xia W. Focusing on UBR5 in hepatocellular carcinoma cells and exact therapy by way of echinacoside nanodelivery. Cell Mol Biol Lett. 2022;27:92.
Jiang S, Li H, Zhang L, Mu W, Zhang Y, Chen T, Wu J, Tang H, Zheng S, Liu Y, et al. Generic Diagramming Platform (GDP): a complete database of high-quality biomedical graphics. Nucleic Acids Res. 2024;29:gkae973.
Speciale A, Muscarà C, Molonia MS, Cristani M, Cimino F, Saija A. Latest advances in glycyrrhetinic acid-functionalized biomaterials for liver cancer-targeting remedy. Molecules. 2022;27:1775.
Duan Y, Jiang F, Li Q, McDowell A, Li Y, Wang Y, Liu S, Zhang C, Pan X. Multifunctional polysaccharide/steel/polyphenol double-crosslinked hydrogel for contaminated wound. Carbohydr Polym. 2024;332: 121912.
Yang W, Zhang Y, Wang J, Li H, Yang H. Glycyrrhetinic acid-cyclodextrin grafted pullulan nanoparticles loaded doxorubicin as a liver focused supply provider. Int J Biol Macromol. 2022;216:789–98.
Zhang J, Zhang M, Ji J, Fang X, Pan X, Wang Y, Wu C, Chen M. Glycyrrhetinic acid-mediated polymeric drug supply concentrating on the acidic microenvironment of hepatocellular carcinoma. Pharm Res. 2015;32:3376–90.
Yan T, Cheng J, Liu Z, Cheng F, Wei X, Huang Y, He J. Acid-sensitive polymeric vector concentrating on to hepatocarcinoma cells by way of glycyrrhetinic acid receptor-mediated endocytosis. Mater Sci Eng C Mater Biol Appl. 2018;87:32–40.
Zhu X, Tsend-Ayush A, Yuan Z, Wen J, Cai J, Luo S, Yao J, Bian J, Yin L, Zhou J, Yao J. Glycyrrhetinic acid-modified TPGS polymeric micelles for hepatocellular carcinoma-targeted remedy. Int J Pharm. 2017;529:451–64.
Daniyal M, Liu B, Wang W. Complete evaluation on graphene oxide to be used in drug supply system. Curr Med Chem. 2020;27:3665–85.
Qu Y, Solar F, He F, Yu C, Lv J, Zhang Q, Liang D, Yu C, Wang J, Zhang X, et al. Glycyrrhetinic acid-modified graphene oxide mediated siRNA supply for enhanced liver-cancer concentrating on remedy. Eur J Pharm Sci. 2019;139: 105036.
Zhu G, Wang B, Feng G, Zhou Z, Li W, Liu W, Su H, Wang W, Wang T, Yu XA. A nano-preparation method to allow the supply of daphnoretin to potentiate the therapeutical efficacy in hepatocellular most cancers. Entrance Pharmacol. 2022;13: 965131.
Wang J, Zhao H, Qiao W, Cheng J, Han Y, Yang X. Nanomedicine-cum-carrier by co-assembly of pure small merchandise for synergistic enhanced antitumor with tissues protecting actions. ACS Appl Mater Interfaces. 2020;12:42537–50.
Zhang Y, Cui Z, Mei H, Xu J, Zhou T, Cheng F, Wang Ok. Angelica sinensis polysaccharide nanoparticles as a focused drug supply system for enhanced remedy of liver most cancers. Carbohydr Polym. 2019;219:143–54.
Cheng X, Yan H, Pang S, Ya M, Qiu F, Qin P, Zeng C, Lu Y. Liposomes as multifunctional nano-carriers for medicinal pure merchandise. Entrance Chem. 2022;10: 963004.
Zhao X, Yang Y, Su X, Xie Y, Liang Y, Zhou T, Wu Y, Di L. Transferrin-modified triptolide liposome concentrating on enhances anti-hepatocellular carcinoma results. Biomedicines. 2023;11:9.
Yu XA, Lu M, Luo Y, Hu Y, Zhang Y, Xu Z, Gong S, Wu Y, Ma XN, Yu BY, Tian J. A cancer-specific activatable theranostic nanodrug for enhanced therapeutic efficacy by way of amplification of oxidative stress. Theranostics. 2020;10:371–83.
Lai S, Wang B, Solar Ok, Li F, Liu Q, Yu XA, Jiang L, Wang L. Self-assembled matrine-PROTAC encapsulating zinc(II) phthalocyanine with GSH-depletion-enhanced ROS era for most cancers remedy. Molecules. 2024;29:1845.
Wu L, Shi Y, Ni Z, Yu T, Chen Z. Preparation of a self-assembled rhein-doxorubicin nanogel concentrating on mitochondria and investigation on its antihepatoma exercise. Mol Pharm. 2022;19:35–50.
Zhang Z, Zhu H, Xie Ok, Lu J, Chen X, Wang H. A self-assembling cytotoxic nanotherapeutic technique for prime drug loading and synergistic supply of molecularly focused therapies. Acta Biomater. 2025;191:398–411.
Lai JD, Berlind JE, Fricklas G, Lie C, Urenda JP, Lam Ok, Sta Maria N, Jacobs R, Yu V, Zhao Z, Ichida JK. KCNJ2 inhibition mitigates mechanical harm in a human mind organoid mannequin of traumatic mind harm. Cell Stem Cell. 2024;31(519–536): e518.
Ding X, Cao S, Wang Q, Du B, Lu Ok, Qi S, Cheng Y, Tuo QZ, Liang W, Lei P. DNALI1 promotes neurodegeneration after traumatic mind harm by way of inhibition of autophagosome-lysosome fusion. Adv Sci. 2024;11: e2306399.
Guo J, Chen X, Wu M, Wang D, Zhao Y, Li Q, Tang G, Che F, Xia Z, Liang Z, et al. Conventional Chinese language medication FYTF-919 (Zhongfeng Xingnao oral prescription) for the therapy of acute intracerebral haemorrhage: a multicentre, randomised, placebo-controlled, double-blind, scientific trial. Lancet. 2024;404:2187–96.
Kealy J, Greene C, Campbell M. Blood-brain barrier regulation in psychiatric issues. Neurosci Lett. 2020;726: 133664.
Wang R, Wang X, Zhao H, Li N, Li J, Zhang H, Di L. Focused supply of hybrid nanovesicles for enhanced mind penetration to attain synergistic remedy of glioma. J Management Launch. 2024;365:331–47.
Li J, Lengthy Q, Ding H, Wang Y, Luo D, Li Z, Zhang W. Progress within the therapy of central nervous system illnesses based mostly on nanosized conventional chinese language medication. Adv Sci. 2024;11: e2308677.
Lengthy Y, Liu S, Wan J, Zhang Y, Li D, Yu S, Shi A, Li N, He F. Mind focused borneol-baicalin liposome improves blood-brain barrier integrity after cerebral ischemia-reperfusion harm by way of inhibiting HIF-1α/VEGF/eNOS/NO sign pathway. Biomed Pharmacother. 2023;160: 114240.
Liang J, Li L, Tian H, Wang Z, Liu G, Duan X, Guo M, Liu J, Zhang W, Good EC, et al. Drug repurposing-based brain-targeting self-assembly nanoplatform utilizing enhanced ferroptosis towards glioblastoma. Small. 2023;19: e2303073.
Lengthy Y, Xiang Y, Liu S, Zhang Y, Wan J, Ci Z, Cui M, Shen L, Li N, Guan Y. Macrophage membrane modified baicalin liposomes enhance mind concentrating on for assuaging cerebral ischemia reperfusion harm. Nanomedicine. 2022;43: 102547.
Chen MH, Liu XZ, Qu XW, Guo RB, Zhang L, Kong L, Yu Y, Liu Y, Zang J, Li XY, Li XT. ApoE-modified liposomes encapsulating resveratrol and salidroside alleviate manifestations of Alzheimer’s illness in APP/PS-1 mice. Drug Dev Ind Pharm. 2023;49:559–71.
Ottonelli I, Sharma A, Ruozi B, Tosi G, Duskey JT, Vandelli MA, Lafuente JV, Nozari A, Muresanu DF, Buzoianu AD, et al. Nanowired supply of curcumin attenuates methamphetamine neurotoxicity and elevates ranges of dopamine and brain-derived neurotrophic issue. Adv Neurobiol. 2023;32:385–416.
Cui J, Wang X, Li J, Zhu A, Du Y, Zeng W, Guo Y, Di L, Wang R. Immune exosomes loading self-assembled nanomicelles traverse the blood-brain barrier for chemo-immunotherapy towards glioblastoma. ACS Nano. 2023.
Zou Y, Wang Y, Xu S, Liu Y, Yin J, Lovejoy DB, Zheng M, Liang XJ, Park JB, Efremov YM, et al. Mind co-delivery of temozolomide and cisplatin for combinatorial glioblastoma chemotherapy. Adv Mater. 2022;34: e2203958.
Zhou J, Li G, Han G, Feng S, Liu Y, Chen J, Liu C, Zhao L, Jin F. Emodin induced necroptosis within the glioma cell line U251 by way of the TNF-α/RIP1/RIP3 pathway. Make investments New Medicine. 2020;38:50–9.
Chen YY, Gong ZC, Zhang MM, Huang ZH. Mind-targeting emodin mitigates ischemic stroke by way of inhibiting AQP4-mediated swelling and neuroinflammation. Transl Stroke Res. 2023;15:818–30.
Yang W, Ip SP, Liu L, Xian YF, Lin ZX. Uncaria rhynchophylla and its main constituents on central nervous system: a evaluation on their pharmacological actions. Curr Vasc Pharmacol. 2020;18:346–57.
Xu R, Wang J, Xu J, Music X, Huang H, Feng Y, Fu C. Rhynchophylline loaded-mPEG-PLGA nanoparticles coated with tween-80 for preliminary examine in Alzheimer’s illness. Int J Nanomed. 2020;15:1149–60.
Li J, Tan T, Zhao L, Liu M, You Y, Zeng Y, Chen D, Xie T, Zhang L, Fu C, Zeng Z. Latest developments in liposome-targeting methods for the therapy of gliomas: a scientific evaluation. ACS Appl Bio Mater. 2020;3:5500–28.
Li Q, Wang C, Hu J, Jiao W, Tang Z, Music X, Wu Y, Dai J, Gao P, Du L, Jin Y. Cannabidiol-loaded biomimetic macrophage membrane vesicles towards post-traumatic stress dysfunction assisted by ultrasound. Int J Pharm. 2023;637: 122872.
Kang S, Duan W, Zhang S, Chen D, Feng J, Qi N. Muscone/RI7217 co-modified upward messenger DTX liposomes enhanced permeability of blood-brain barrier and concentrating on glioma. Theranostics. 2020;10:4308–22.
Khafaga DSR, El-Khawaga AM, Elfattah Mohammed RA, Abdelhakim HK. Inexperienced synthesis of nano-based drug supply techniques developed for hepatocellular carcinoma therapy: a evaluation. Mol Biol Rep. 2023;50:10351–64.
Qi N, Duan W, Gao D, Ma N, Zhang J, Feng J, Li A. “Information” of muscone modification enhanced brain-targeting efficacy and anti-glioma impact of lactoferrin modified DTX liposomes. Bioeng Transl Med. 2023;8: e10393.
Chen R, Zhu C, Xu L, Gu Y, Ren S, Bai H, Zhou Q, Liu X, Lu S, Bi X, et al. An injectable peptide hydrogel with wonderful self-healing capability to repeatedly launch salvianolic acid B for myocardial infarction. Biomaterials. 2021;274: 120855.
Zhang S, Asghar S, Yang L, Hu Z, Chen Z, Shao F, Xiao Y. Borneol and poly (ethylene glycol) twin modified BSA nanoparticles as an itraconazole automobile for mind concentrating on. Int J Pharm. 2020;575: 119002.
Wang J, Kong L, Guo RB, He SY, Liu XZ, Zhang L, Liu Y, Yu Y, Li XT, Cheng L. Multifunctional icariin and tanshinone IIA co-delivery liposomes with potential utility for Alzheimer’s illness. Drug Deliv. 2022;29:1648–62.
Gu J, Yan C, Yin S, Wu H, Liu C, Xue A, Lei X, Zhang N, Geng F. Erythrocyte membrane-coated nanocarriers modified by TGN for Alzheimer’s illness. J Management Launch. 2024;366:448–59.
Elzoghby AO, Abdelmoneem MA, Hassanin IA, Abd Elwakil MM, Elnaggar MA, Mokhtar S, Fang JY, Elkhodairy KA. Lactoferrin, a multi-functional glycoprotein: lively therapeutic, drug nanocarrier and concentrating on ligand. Biomaterials. 2020;263: 120355.
Bian X, Yang L, Jiang D, Grippin AJ, Ma Y, Wu S, Wu L, Wang X, Tang Z, Tang Ok, et al. Regulation of cerebral blood circulation boosts exact mind concentrating on of vinpocetine-derived ionizable-lipidoid nanoparticles. Nat Commun. 2024;15:3987.
Zhao X, Williamson T, Gong Y, Epstein JA, Fan Y. Immunomodulatory remedy for ischemic coronary heart illness. Circulation. 2024;150:1050–8.
Praz F, Beyersdorf F, Haugaa Ok, Prendergast B. Valvular coronary heart illness: from mechanisms to administration. Lancet. 2024;403:1576–89.
Cheang I, Yao W, Zhou Y, Zhu X, Ni G, Lu X, Liao S, Gao R, Zhou F, Shen J, et al. The normal Chinese language medication Qiliqiangxin in coronary heart failure with diminished ejection fraction: a randomized, double-blind, placebo-controlled trial. Nat Med. 2024;30:2295–302.
Li H, Zhu J, Xu YW, Mou FF, Shan XL, Wang QL, Liu BN, Ning Ok, Liu JJ, Wang YC, et al. Notoginsenoside R1-loaded mesoporous silica nanoparticles concentrating on the location of harm by way of inflammatory cells improves coronary heart restore after myocardial infarction. Redox Biol. 2022;54: 102384.
Feng J, Xing M, Qian W, Qiu J, Liu X. An injectable hydrogel combining medication and matrix with anti-inflammatory and pro-angiogenic properties for potential therapy of myocardial infarction. Regen Biomater. 2023;10:rbad036.
Pillai SC, Borah A, Le MNT, Kawano H, Hasegawa Ok, Kumar DS. Co-delivery of curcumin and bioperine by way of PLGA nanoparticles to forestall atherosclerotic foam cell formation. Pharmaceutics. 2021;13:1420.
Li H, Sureda A, Devkota HP, Pittalà V, Barreca D, Silva AS, Tewari D, Xu S, Nabavi SM. Curcumin, the golden spice in treating cardiovascular illnesses. Biotechnol Adv. 2020;38: 107343.
Aziz B, Aziz I, Khurshid A, Raoufi E, Esfahani FN, Jalilian Z, Mozafari MR, Taghavi E, Ikram M. An summary of potential pure photosensitizers in most cancers photodynamic remedy. Biomedicines. 2023;11:224.
Xu L, Solar Z, Xing Z, Liu Y, Zhao H, Tang Z, Luo Y, Hao S, Li Ok. Cur@SF NPs alleviate Friedreich’s ataxia in a mouse mannequin by way of synergistic iron chelation and antioxidation. J Nanobiotechnol. 2022;20:118.
Huang Z, Solar Ok, Luo Z, Zhang J, Zhou H, Yin H, Liang Z, You J. Spleen-targeted supply techniques and methods for spleen-related illnesses. J Management Launch. 2024;370:773–97.
Cruz de Casas P, Knöpper Ok, Dey Sarkar R, Kastenmüller W. Identical but totally different—how lymph node heterogeneity impacts immune responses. Nat Rev Immunol. 2024;24:358–74.
Zhou H, Han X, Huang C, Wu H, Hu Y, Chen C, Tao J. Train-induced adaptive response of various immune organs throughout ageing. Ageing Res Rev. 2024;102: 102573.
Hu T, Liu CH, Lei M, Zeng Q, Li L, Tang H, Zhang N. Metabolic regulation of the immune system in well being and illnesses: mechanisms and interventions. Sign Transduct Goal Ther. 2024;9:268.
Yu X, Dai Y, Zhao Y, Qi S, Liu L, Lu L, Luo Q, Zhang Z. Melittin-lipid nanoparticles goal to lymph nodes and elicit a systemic anti-tumor immune response. Nat Commun. 2020;11:1110.
Shrivastava S, Kaur CD. Improvement of andrographolide-loaded stable lipid nanoparticles for lymphatic concentrating on: formulation, optimization, characterization, in vitro, and in vivo analysis. Drug Deliv Transl Res. 2023;13:658–74.
Li S, Wang Y, Wu M, Younis MH, Olson AP, Barnhart TE, Engle JW, Zhu X, Cai W. Spleen-targeted glabridin-loaded nanoparticles regulate polarization of monocyte/macrophage (M(o) /M(φ) ) for the therapy of cerebral ischemia-reperfusion harm. Adv Mater. 2022;34: e2204976.
Jaber FA. Quercetin mitigates oxidative stress, irritation, apoptosis, and histopathological alterations induced by continual titanium dioxide nanoparticle publicity within the rat spleen. Microsc Microanal. 2023;29:1718–29.
Vaughn VM, Dickson RP, Horowitz JK, Flanders SA. Neighborhood-acquired pneumonia: a evaluation. JAMA. 2024;332:1282–95.
Xiong H, Du C, Ye J, Zhang H, Qin Y, Zeng F, Music R, Shi C, Guo H, Chen J, et al. Therapeutic co-assemblies for synergistic NSCLC therapy by way of twin topoisomerase I and tubulin inhibitors. J Management Launch. 2024;377:485–94.
Music Y, Cai L, Tian Z, Wu Y, Chen J. Phytochemical curcumin-coformulated, silver-decorated melanin-like polydopamine/mesoporous silica composites with improved antibacterial and chemotherapeutic results towards drug-resistant most cancers cells. ACS Omega. 2020;5:15083–94.
Li Y, Guo C, Chen Q, Su Y, Guo H, Liu R, Solar C, Mi S, Wang J, Chen D. Enchancment of pneumonia by curcumin-loaded bionanosystems based mostly on platycodon grandiflorum polysaccharides by way of calming cytokine storm. Int J Biol Macromol. 2022;202:691–706.
Chen YB, Zhang YB, Wang YL, Kaur P, Yang BG, Zhu Y, Ye L, Cui YL. A novel inhalable quercetin-alginate nanogel as a promising remedy for acute lung harm. J Nanobiotechnol. 2022;20:272.
Wang D, Mehrabi Nasab E, Athari SS. Research impact of Baicalein encapsulated/loaded Chitosan-nanoparticle on allergic bronchial asthma pathology in mouse mannequin. Saudi J Biol Sci. 2021;28:4311–7.
Music S, Ding L, Liu G, Chen T, Zhao M, Li X, Li M, Qi H, Chen J, Wang Z, et al. The protecting results of baicalin for respiratory illnesses: an replace and future views. Entrance Pharmacol. 2023;14:1129817.
Xu F, Li M, Que Z, Su M, Yao W, Zhang Y, Luo B, Li Y, Zhang Z, Tian J. Mixed chemo-immuno-photothermal remedy based mostly on ursolic acid/astragaloside IV-loaded hyaluronic acid-modified polydopamine nanomedicine inhibiting the expansion and metastasis of non-small cell lung most cancers. J Mater Chem B. 2023;11:3453–72.
Wang Y, Wang B, Yang X. The examine of mobile mechanism of triptolide within the therapy of most cancers, bone loss and heart problems and triptolide’s toxicity. Curr Stem Cell Res Ther. 2020;15:18–23.
Ren Q, Li M, Deng Y, Lu A, Lu J. Triptolide supply: nanotechnology-based provider techniques to reinforce efficacy and restrict toxicity. Pharmacol Res. 2021;165: 105377.
Wu Q, Ou H, Shang Y, Zhang X, Wu J, Fan F. Nanoscale formulations: incorporating curcumin into mixture methods for the therapy of lung most cancers. Drug Des Devel Ther. 2021;15:2695–709.
Xiong D, Gao F, Shao J, Pan Y, Wang S, Wei D, Ye S, Chen Y, Chen R, Yue B, et al. Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial sort 2 cell senescence to alleviate pulmonary fibrosis by way of the p38/p53/p21 pathway. Entrance Pharmacol. 2023;14:1141800.
Perico L, Remuzzi G, Benigni A. Sirtuins in kidney well being and illness. Nat Rev Nephrol. 2024;20:313–29.
Li H, Zhao X, Zheng L, Wang X, Lin S, Shen J, Ren H, Li Y, Qiu Q, Wang Z. Bruceine A protects towards diabetic kidney illness by way of inhibiting galectin-1. Kidney Int. 2022;102:521–35.
Wu W, Wang W, Liang L, Chen J, Wei B, Huang XR, Wang X, Yu X, Lan HY. Therapy with quercetin inhibits SARS-CoV-2 N protein-induced acute kidney harm by blocking Smad3-dependent G1 cell-cycle arrest. Mol Ther. 2023;31:344–61.
Wang G, Li Q, Chen D, Wu B, Wu Y, Tong W, Huang P. Kidney-targeted rhein-loaded liponanoparticles for diabetic nephropathy remedy by way of measurement management and enhancement of renal mobile uptake. Theranostics. 2019;9:6191–208.
Yongvongsoontorn N, Chung JE, Gao SJ, Bae KH, Yamashita A, Tan MH, Ying JY, Kurisawa M. Provider-enhanced anticancer efficacy of sunitinib-loaded inexperienced tea-based micellar nanocomplex past tumor-targeted supply. ACS Nano. 2019;13:7591–602.
Liu Q, Chen X, Kan M, Yang J, Gong Q, Jin R, Dai Y, Jin J, Zang H. Gypenoside XLIX loaded nanoparticles concentrating on remedy for renal fibrosis and its mechanism. Eur J Pharmacol. 2021;910: 174501.
Zhou S, Lu S, Guo S, Zhao L, Han Z, Li Z. Protecting impact of ginsenoside Rb1 nanoparticles towards contrast-induced nephropathy by inhibiting excessive mobility group field 1 gene/toll-like receptor 4/NF-kappaB signaling pathway. J Biomed Nanotechnol. 2021;17:2085–98.
Benson AB, Venook AP, Adam M, Chang G, Chen YJ, Ciombor KK, Cohen SA, Cooper HS, Deming D, Garrido-Laguna I, et al. Colon most cancers, model 3.2024, NCCN scientific follow tips in oncology. J Natl Compr Canc Netw. 2024;22:e240029.
Zou T, Lu W, Mezhuev Y, Lan M, Li L, Liu F, Cai T, Wu X, Cai Y. A evaluation of nanoparticle drug supply techniques conscious of endogenous breast most cancers microenvironment. Eur J Pharm Biopharm. 2021;166:30–43.
Wang R, Kumar P, Reda M, Wallstrum AG, Crumrine NA, Ngamcherdtrakul W, Yantasee W. Nanotechnology purposes in breast most cancers immunotherapy. Small. 2024;20: e2308639.
Solar S, Zhang Ok, Wang Y, Zhou Z, Wang L, Zhao H, Zhang Y. Pharmacodynamic construction of deer antler base protein and its mammary gland hyperplasia inhibition mechanism by mediating Raf-1/MEK/ERK signaling pathway activation. Meals Funct. 2023;14:3319–31.
Yue G, Wang C, Liu B, Wu M, Huang Y, Guo Y, Ma Q. Liposomes co-delivery system of doxorubicin and astragaloside IV co-modified by folate ligand and octa-arginine polypeptide for anti-breast most cancers. RSC Adv. 2020;10:11573–81.
Wang B, Guo C, Liu Y, Han G, Li Y, Zhang Y, Xu H, Chen D. Novel nano-pomegranates based mostly on astragalus polysaccharides for concentrating on ERα-positive breast most cancers and multidrug resistance. Drug Deliv. 2020;27:607–21.
Chen H, Huang S, Wang H, Chen X, Zhang H, Xu Y, Fan W, Pan Y, Wen Q, Lin Z, et al. Preparation and characterization of paclitaxel palmitate albumin nanoparticles with excessive loading efficacy: an in vitro and in vivo anti-tumor examine in mouse fashions. Drug Deliv. 2021;28:1067–79.
Huang C, Chen T, Zhu D, Huang Q. Enhanced tumor concentrating on and radiotherapy by quercetin loaded biomimetic nanoparticles. Entrance Chem. 2020;8:225.
Tian J, Chen Ok, Zhang Q, Qiu C, Tong H, Huang J, Hao M, Chen J, Zhao W, Wong Y-Ok, et al. Mechanism of self-assembled celastrol-erianin nanomedicine for therapy of breast most cancers. Chem Eng J. 2024;1: 155709.
Chen R, Ni S, Chen W, Liu M, Feng J, Hu Ok. Improved anti-triple detrimental breast most cancers results of docetaxel by RGD-modified lipid-core micelles. Int J Nanomed. 2021;16:5265–79.
Sui F, Fang Z, Li L, Wan X, Zhang Y, Cai X. pH-triggered “PEG” sheddable and folic acid-targeted nanoparticles for docetaxel supply in breast most cancers therapy. Int J Pharm. 2023;644: 123293.
He Z, Zhang Y, Feng N. Cell membrane-coated nanosized lively focused drug supply techniques homing to tumor cells: a evaluation. Mater Sci Eng C Mater Biol Appl. 2020;106: 110298.
Zhang X, Gao H, Wei D, Pei X, Zhang Y, Wang J, Ding D, Chang J, Wu X. ROS responsive nanoparticles encapsulated with pure medication transform autophagy homeostasis in breast most cancers. ACS Appl Mater Interfaces. 2023;15:29827–40.
Fu M, Tang W, Liu JJ, Gong XQ, Kong L, Yao XM, Jing M, Cai FY, Li XT, Ju RJ. Mixture of focused daunorubicin liposomes and focused emodin liposomes for therapy of invasive breast most cancers. J Drug Goal. 2020;28:245–58.
Hong C, Liang J, Xia J, Zhu Y, Guo Y, Wang A, Lu C, Ren H, Chen C, Li S, et al. One stone 4 birds: a novel liposomal supply system multi-functionalized with ginsenoside Rh2 for tumor concentrating on remedy. Nanomicro Lett. 2020;12:129.
Lan J, Chen L, Li Z, Liu L, Zeng R, He Y, Shen Y, Zhang T, Ding Y. Multifunctional biomimetic liposomes with improved tumor-targeting for TNBC therapy by mixture of chemotherapy. Antiangiogen Immunother Adv Healthc Mater. 2024;13: e2400046.
Wu Y, Chen R, Ni S, Hu Ok. Biomimetic, “nano-spears” for CAFs-targeting: splintered three “shields” with enhanced cisplatin anti-TNBC effectivity. J Management Launch. 2024;370:556–69.
Audisio A, Fazio R, Dapra V, Assaf I, Hendlisz A, Sclafani F. Neoadjuvant chemotherapy for early-stage colon most cancers. Most cancers Deal with Rev. 2024;123: 102676.
Bai S, Solar Y, Cheng Y, Ye W, Jiang C, Liu M, Ji Q, Zhang B, Mei Q, Liu D, Zhou S. MCP mediated lively concentrating on calcium phosphate hybrid nanoparticles for the therapy of orthotopic drug-resistant colon most cancers. J Nanobiotechnol. 2021;19:367.
Pu X, Ye N, Lin M, Chen Q, Dong L, Xu H, Luo R, Han X, Qi S, Nie W, et al. β-1,Three-D-Glucan based mostly yeast cell wall system loaded emodin with dual-targeting layers for ulcerative colitis therapy. Carbohydr Polym. 2021;273: 118612.
Bao H, Zheng N, Li Z, Zhi Y. Synergistic impact of tangeretin and atorvastatin for colon most cancers mixture remedy: focused supply of those twin medicine utilizing RGD peptide embellished nanocarriers. Drug Des Devel Ther. 2020;14:3057–68.
Zu M, Music H, Zhang J, Chen Q, Deng S, Canup BSB, Yuan Y, Xiao B. Lycium barbarum lipid-based edible nanoparticles defend towards experimental colitis. Colloids Surf B Biointerfaces. 2020;187: 110747.
Han X, Luo R, Qi S, Wang Y, Dai L, Nie W, Lin M, He H, Ye N, Fu C, et al. “Twin delicate supramolecular curcumin nanoparticles” in “superior yeast particles” mediate macrophage reprogramming, ROS scavenging and irritation decision for ulcerative colitis therapy. J Nanobiotechnol. 2023;21:321.
Yalikong A, Li XQ, Zhou PH, Qi ZP, Li B, Cai SL, Zhong YS. A triptolide loaded HER2-targeted nano-drug supply system considerably suppressed the proliferation of HER2-positive and BRAF mutant colon most cancers. Int J Nanomed. 2021;16:2323–35.
Zhang M, Viennois E, Prasad M, Zhang Y, Wang L, Zhang Z, Han MK, Xiao B, Xu C, Srinivasan S, Merlin D. Edible ginger-derived nanoparticles: a novel therapeutic method for the prevention and therapy of inflammatory bowel illness and colitis-associated most cancers. Biomaterials. 2016;101:321–40.
Xu Y, Chen Z, Hao W, Yang Z, Farag M, Vong CT, Wang Y, Wang S. Berberine and magnolol exert cooperative results on ulcerative colitis in mice by self-assembling into carrier-free nanostructures. J Nanobiotechnol. 2024;22:538.
Huang F, Zhang Q, Xiao J, Zhang X, Han X, Shi X, Hu J, Li L, Qian X. Most cancers cell membrane-coated gambogic acid nanoparticles for efficient anticancer vaccination by activating dendritic cells. Int J Nanomed. 2023;18:2261–73.
Tian X, Wang P, Li T, Huang X, Guo W, Yang Y, Yan M, Zhang H, Cai D, Jia X, et al. Self-assembled pure phytochemicals for synergistically antibacterial utility from the enlightenment of conventional Chinese language medication mixture. Acta Pharm Sin B. 2020;10:1784–95.
Lu J, Wang Z, Cai D, Lin X, Huang X, Yuan Z, Zhang Y, Lei H, Wang P. Provider-free binary self-assembled nanomedicines originated from conventional herb medication with multifunction to speed up MRSA-infected wound therapeutic by antibacterial, anti-inflammation and selling angiogenesis. Int J Nanomed. 2023;18:4885–906.
Huang X, Wang P, Li T, Tian X, Guo W, Xu B, Huang G, Cai D, Zhou F, Zhang H, Lei H. Self-assemblies based mostly on conventional medication berberine and cinnamic acid for adhesion-induced inhibition multidrug-resistant Staphylococcus aureus. ACS Appl Mater Interfaces. 2020;12:227–37.
Li T, Wang P, Guo W, Huang X, Tian X, Wu G, Xu B, Li F, Yan C, Liang XJ, Lei H. Pure berberine-based Chinese language herb medication assembled nanostructures with modified antibacterial utility. ACS Nano. 2019;13:6770–81.
Shen Y, Zou Y, Chen X, Li P, Rao Y, Yang X, Solar Y, Hu H. Antibacterial self-assembled nanodrugs composed of berberine derivatives and rhamnolipids towards Helicobacter pylori. J Management Launch. 2020;328:575–86.
Gao S, Zheng H, Xu S, Kong J, Gao F, Wang Z, Li Y, Dai Z, Jiang X, Ding X, Lei H. Novel pure carrier-free self-assembled nanoparticles for therapy of ulcerative colitis by balancing immune microenvironment and intestinal barrier. Adv Healthc Mater. 2023;12: e2301826.
Fu S, Yi X, Li Y, Li Y, Qu X, Miao P, Xu Y. Berberine and chlorogenic acid-assembled nanoparticles for extremely environment friendly inhibition of multidrug-resistant Staphylococcus aureus. J Hazard Mater. 2024;473: 134680.
Zhu W, Yu M, Wang M, Zhang M, Hai Z. Sequential self-assembly and launch of a camptothecin prodrug for tumor-targeting remedy. Nanoscale. 2024. https://doi.org/10.1039/D4NR03519D.
Duan Y, Xu P, Ge P, Chen L, Chen Y, Kankala RK, Wang S, Chen A. NIR-responsive carrier-free nanoparticles based mostly on berberine hydrochloride and indocyanine inexperienced for synergistic antibacterial remedy and selling contaminated wound therapeutic. Regen Biomater. 2023;10:rbad076.
Li L, Cui H, Li T, Qi J, Chen H, Gao F, Tian X, Mu Y, He R, Lv S, et al. Synergistic impact of berberine-based chinese language medication assembled nanostructures on diarrhea-predominant irritable bowel syndrome In Vivo. Entrance Pharmacol. 2020;11:1210.
Tang Z, Zhang X, Meng S, Yi X, Liu Y, Wu Ok, Li Y, Peng S, Guo H, Du M, et al. Cell membrane camouflaged and ROS responsive nanosomes for focused endometriosis remedy by way of reversing inflammatory, low-autophagy, and immunotolerant microenvironment. Chem Eng J. 2024;493:9.
Wang MZ, He X, Yu Z, Wu H, Yang TH. A nano drug supply system based mostly on angelica sinensis polysaccharide for mixture of chemotherapy and immunotherapy. Molecules. 2020;25:3096.
Solar G, Solar Ok, Solar J. Mixture prostate most cancers remedy: prostate-specific membranes antigen focused, pH-sensitive nanoparticles loaded with doxorubicin and tanshinone. Drug Deliv. 2021;28:1132–40.
Wei Z, Wang H, Xin G, Zeng Z, Li S, Ming Y, Zhang X, Xing Z, Li L, Li Y, et al. A pH-sensitive prodrug nanocarrier based mostly on diosgenin for doxorubicin supply to effectively inhibit tumor metastasis. Int J Nanomed. 2020;15:6545–60.
Li Z, Zhang Y, Zhu C, Guo T, Xia Q, Hou X, Liu W, Feng N. Folic acid modified lipid-bilayer coated mesoporous silica nanoparticles co-loading paclitaxel and tanshinone IIA for the therapy of acute promyelocytic leukemia. Int J Pharm. 2020;586: 119576.
Rehan T, Tahir A, Sultan A, Alabbosh KF, Waseem S, Ul-Islam M, Khan KA, Ibrahim EH, Ullah MW, Shah N. Mitigation of benzene-induced haematotoxicity in sprague dawley rats by way of plant-extract-loaded silica nanobeads. Toxics. 2023;11:865.
Cao X, Deng T, Zhu Q, Wang J, Shi W, Liu Q, Yu Q, Deng W, Yu J, Wang Q, et al. Photothermal remedy mediated hybrid membrane derived nano-formulation for enhanced most cancers remedy. AAPS PharmSciTech. 2023;24:146.
Fu X, Ni Y, Wang G, Nie R, Wang Y, Yao R, Yan D, Guo M, Li N. Synergistic and Lengthy-Lasting Wound Dressings Promote Multidrug-Resistant Staphylococcus Aureus-Contaminated Wound Therapeutic. Int J Nanomed. 2023;18:4663–79.
Brecht Ok, Riebel V, Couttet P, Paech F, Wolf A, Chibout SD, Pognan F, Krahenbuhl S, Uteng M. Mechanistic insights into selective killing of OXPHOS-dependent most cancers cells by arctigenin. Toxicol In Vitro. 2017;40:55–65.
Zhang X, Liu H, Li N, Li J, Wang M, Ren X. A (conventional chinese language medication) TCM-inspired doxorubicin resistance reversing technique: preparation, characterization, and utility of a co-loaded pH-sensitive liposome. AAPS PharmSciTech. 2023;24:181.
Zhao X, Shi A, Ma Q, Yan X, Bian L, Zhang P, Wu J. Nanoparticles ready from pterostilbene cut back blood glucose and enhance diabetes problems. J Nanobiotechnology. 2021;19:191.
Wang M, Yin F, Kong L, Yang L, Solar H, Solar Y, Yan G, Han Y, Wang X. Chinmedomics: a potent device for the analysis of conventional Chinese language medication efficacy and identification of its lively elements. Chin Med. 2024;19:47.
Xu HY, Zhang YQ, Liu ZM, Chen T, Lv CY, Tang SH, Zhang XB, Zhang W, Li ZY, Zhou RR, et al. ETCM: an encyclopaedia of conventional Chinese language medication. Nucleic Acids Res. 2019;47:D976–82.
Li X, Zhu R, Liu Q, Solar H, Sheng H, Zhu L. Results of conventional Chinese language medication polysaccharides on continual illnesses by modulating intestine microbiota: a evaluation. Int J Biol Macromol. 2024;282: 136691.
Wang M, Yao PF, Solar PY, Liang W, Chen XJ. Key high quality components for Chinese language natural medicines coming into the EU market. Chin Med. 2022;17:29.
Fang C, Li Y, He G, Gan RY, Luo F, Lei L, Hou X, Ye Y. Silk fibroin microneedles loaded with epigallocatechin gallate mitigate atrazine-induced testicular toxicity. J Hazard Mater. 2024;480: 136252.
Zhang J, Hu Ok, Di L, Wang P, Liu Z, Zhang J, Yue P, Music W, Zhang J, Chen T, et al. Conventional natural medication and nanomedicine: converging disciplines to enhance therapeutic efficacy and human well being. Adv Drug Deliv Rev. 2021;178: 113964.
Qu C, Li QP, Su ZR, Ip SP, Yuan QJ, Xie YL, Xu QQ, Yang W, Huang YF, Xian YF, Lin ZX. Nano-Honokiol ameliorates the cognitive deficits in TgCRND8 mice of Alzheimer’s illness by way of inhibiting neuropathology and modulating intestine microbiota. J Adv Res. 2022;35:231–43.
Shang S, Li X, Wang H, Zhou Y, Pang Ok, Li P, Liu X, Zhang M, Li W, Li Q, Chen X. Focused remedy of kidney illness with nanoparticle drug supply supplies. Bioact Mater. 2024;37:206–21.
Shang Q, Liu W, Leslie F, Yang J, Guo M, Solar M, Zhang G, Zhang Q, Wang F. Nano-formulated supply of lively elements from conventional Chinese language natural medicines for most cancers immunotherapy. Acta Pharm Sin B. 2024;14:1525–41.
Gao L, Zhang L, He F, Chen J, Zhao M, Li S, Wu H, Liu Y, Zhang Y, Ping Q, et al. Surfactant assisted rapid-release liposomal methods improve the antitumor effectivity of bufalin by-product and cut back cardiotoxicity. Int J Nanomed. 2021;16:3581–98.
Jin M, Hou Y, Quan X, Chen L, Gao Z, Huang W. Good polymeric nanoparticles with pH-responsive and PEG-detachable properties (II): co-delivery of paclitaxel and VEGF siRNA for synergistic breast most cancers remedy in mice. Int J Nanomed. 2021;16:5479–94.
Dang W, Guo P, Music X, Zhang Y, Li N, Yu C, Xing B, Liu R, Jia X, Zhang Q, et al. Nuclear focused peptide mixed with gambogic acid for synergistic therapy of breast most cancers. Entrance Chem. 2021;9: 821426.
Music M, Dong S, An X, Zhang W, Shen N, Li Y, Guo C, Liu C, Li X, Chen S. Erythrocyte-biomimetic nanosystems to enhance antitumor results of paclitaxel on epithelial cancers. J Management Launch. 2022;345:744–54.
Pan B, Wu F, Lu S, Lu W, Cao J, Cheng F, Ou M, Chen Y, Zhang F, Wu G, Mei L. Luteolin-loaded hyaluronidase nanoparticles with deep tissue penetration functionality for idiopathic pulmonary fibrosis therapy. Small Strategies. 2024;2024:e2400980.
Yu X, Wang J, Wang T, Music S, Su H, Huang H, Luo P. Ellagic acid-enhanced biocompatibility and bioactivity in multilayer core-shell gold nanoparticles for ameliorating myocardial infarction harm. J Nanobiotechnol. 2024;22:554.
Zhu W, Wu Y, Li X, Yang H, He F, Ma J, Wei J, Leng L. A stroke organoids-multiomics platform to check harm mechanism and drug response. Bioactive Mater. 2025;44:68–81.
Gou H, Su H, Liu D, Wong CC, Shang H, Fang Y, Zeng X, Chen H, Li Y, Huang Z, et al. Conventional medication Pien Tze huang suppresses colorectal tumorigenesis by way of restoring intestine microbiota and metabolites. Gastroenterology. 2023;165:1404–19.
Joyce P, Allen CJ, Alonso MJ, Ashford M, Bradbury MS, Germain M, Kavallaris M, Langer R, Lammers T, Peracchia MT, et al. A translational framework to DELIVER nanomedicines to the clinic. Nat Nanotechnol. 2024;19:1597–611.
Ma P, Wang G, Males Ok, Li C, Gao N, Li L. Advances in scientific utility of nanoparticle-based remedy for most cancers therapy: a scientific evaluation. Nano TransMed. 2024;3:35.
Gadekar V, Borade Y, Kannaujia S, Rajpoot Ok, Anup N, Tambe V, Kalia Ok, Tekade RK. Nanomedicines accessible available in the market for scientific interventions. J Management Launch. 2021;330:372–97.
Gawne PJ, Ferreira M, Papaluca M, Grimm J, Decuzzi P. New alternatives and previous challenges within the scientific translation of nanotheranostics. Nat Rev Mater. 2023;8:783–98.