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Thursday, November 7, 2024

Peptide-Enhanced Nanocellulose for Excessive-Efficiency Supplies


A latest research performed by researchers from the Politecnico di Milano, in collaboration with Aalto College, the VTT-Technical Analysis Centre in Finland, and the SCITEC Institute of the CNR, aimed to develop hydrophobic paper by leveraging the mechanical properties and water resistance of cellulose nanofibers. This analysis seeks to create a sustainable, high-performance materials appropriate for packaging and biomedical purposes.

Peptide-Enhanced Nanocellulose for Excessive-Efficiency Supplies
Schematic illustration of the hybrid community based mostly on CNF and DFNKF, highlighting the residues exploited for functionalization and interplay with CNF. The halogenated derivatives, DF(I)NKF and DF(F5)NKF, have been obtained by substituting the Phe within the second place with the corresponding halogenated amino acids. Credit score: Journal of Supplies Chemistry B (2024).

This strategy utilized supramolecular strategies, combining brief protein chains (peptide sequences) with cellulose nanofibers with out chemically modifying them. Such hydrophobic paper might probably exchange petroleum-based merchandise sooner or later.

Cellulose nanofibers (CNFs), derived from cellulose—a renewable and biodegradable materials—are well-known for his or her energy and flexibility. On this research, researchers from the SupraBioNanoLab on the “Giulio Natta” Division of Chemistry, Supplies, and Chemical Engineering on the Politecnico di Milano demonstrated that the properties of cellulose nanofibers might be considerably enhanced by means of the incorporation of small proteins known as peptides, all with out chemical modification.

Our supramolecular strategy concerned including small sequences of peptides, which bind onto the nanofibers and so enhance their mechanical efficiency and water resistance. The outcomes of the research confirmed that even minimal portions of peptides (lower than 0.1 %) can considerably enhance the mechanical properties of the hybrid supplies produced, giving them larger resistance to emphasize.

Elisa Marelli, Examine Co-Writer, Politecnico di Milano

The researchers additionally evaluated the impact of incorporating fluorine atoms into the peptide sequences. This modification allowed the creation of a structured hydrophobic movie on the fabric, enhancing its water resistance whereas sustaining its biocompatibility and sustainability.

This advance opens up new alternatives for creating biomaterials that may compete with petroleum-derived supplies by way of efficiency, attaining the identical high quality and effectivity whereas lowering environmental influence. These hybrid supplies are very appropriate for sustainable packaging, the place resistance to moisture is important, and in addition to be used in biomedical units, due to their biocompatibility.

Pierangelo Metrangolo, Examine Co-Writer, Politecnico di Milano

Journal Reference:

Marchetti, A., et al. (2024) Nanocellulose-Quick Peptide Self-Meeting for Improved Mechanical Energy and Barrier Efficiency. Journal of Supplies Chemistry B. doi.org/10.1039/d4tb01359j.

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